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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Keratosis Be The Symptoms Of Cancer?

my husband had part of his tongue removed with a flap placed in 2007 due to squamous cell cancer of the tongue. He has followed up with his ENT MD every six months.....but on his last visit they decided to biopsy a small area close to the original site...due to small "white" growths. The biopsy revealed keratosis with moderate dysplagia. Is this cause for concern?
Wed, 10 Dec 2014
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Pulmonologist 's  Response
Thanks for your question on HCM.
Tongue cancer is very notorious for local recurrence.
The biopsy report you have mentioned is suggestive of malignant recurrence.
The cells in histopathology termes as dysplastic when they are malignant.
When morphology of cells is not normal, they have high nucleo cytoplasmic ratio with irregular borders and granules in cytoplasm tgan they are termed as dysplastic cells. So keratosis is not cancer but keratosis with dysplasia is cancer.
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Can Keratosis Be The Symptoms Of Cancer?

Thanks for your question on HCM. Tongue cancer is very notorious for local recurrence. The biopsy report you have mentioned is suggestive of malignant recurrence. The cells in histopathology termes as dysplastic when they are malignant. When morphology of cells is not normal, they have high nucleo cytoplasmic ratio with irregular borders and granules in cytoplasm tgan they are termed as dysplastic cells. So keratosis is not cancer but keratosis with dysplasia is cancer.