Hi, Cyclo Progynova contains both norgestrel and estradiol valerate that acts as a hormone replacement therapy to relieve symptoms of the menopause like hot flushes, sweats, depressive moods, headache etc., and used in the treatment of primary as well as secondary amenorrhea, menstrual cycle irregularities and in the prevention of postmenopausal osteoporosis. But like other medications this medication has some side effects of its own. During the first few months of treatment with Cyclo Progynova, you may notice delayed cycles, spotting or breakthrough bleeding between periods, heavy bleeding during periods etc. But these side effects usually go away over time as the body adjusts to this medication. So, you should follow your doctor s instructions and take this medication in the dose and duration as directed by the prescribing doctor. If you have still any query then you can consult your doctor for further details. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Zubayer Alam, General And Family Physician