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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Steroid Cause Abnormal Pap Smear?

I am 58 yrs old, post-menapausal for 10 yrs. Years ago I was given high doses of steroids due to MS,(optic neuritis)via IV. A few months later I had an abnormal Pap smear. The test was normal a month later. That was 19 years ago. I still wonder about this as my husband and I never had another partner. We were high school sweethearts. Did the steroids have a role in this abnormal Pap? Thank you.
Mon, 2 Mar 2015
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Infectious Diseases Specialist 's  Response
Hello dear,

Thank you for your contact to health care magic.

I read and understand your concern.

I am Dr Arun Tank answering your concern.

No, short term steroids never causes any such effects on the pap smear. But if you take it for long period than it can cause such effect.

Other cause for the abnormal pap is a malignancy. This abnormal pap should be rated with clinical condition or USG examination.

If the pap smear grade is very abnormal than you should do hysterectomy.

Infection may cause abnormal pap so you can also retest after the infection is cured otherwise diagnosis can be wrong.

I will be happy to answer your further concern on bit.ly/DrArun.

Thank you,
Dr Arun Tank
Infectious diseases specialist,
HCM.
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Can Steroid Cause Abnormal Pap Smear?

Hello dear, Thank you for your contact to health care magic. I read and understand your concern. I am Dr Arun Tank answering your concern. No, short term steroids never causes any such effects on the pap smear. But if you take it for long period than it can cause such effect. Other cause for the abnormal pap is a malignancy. This abnormal pap should be rated with clinical condition or USG examination. If the pap smear grade is very abnormal than you should do hysterectomy. Infection may cause abnormal pap so you can also retest after the infection is cured otherwise diagnosis can be wrong. I will be happy to answer your further concern on bit.ly/DrArun. Thank you, Dr Arun Tank Infectious diseases specialist, HCM.