Just curious, I have had a ton of tests done lately and the one worrying me is a positive anti-smooth muscle antibody . My blood tests are negative for lupus, vasculitis , sjorgren s syndrome, my liver enzymes are fine. I just had my second baby about 8 months ago. Could I have a positive Anti-SMA with no real problems? Or does it always conclusively indicate something else? Primarily, I have arthritis like joint pain on the left side of my body (pointer finger, knee, ankle) and I also have Hashimoto s Thyroiditis. I was also recently treated with Flagyl for Blastocystic Hominis and with Albenza for a potential worm infestation.