Hi I am a 26 year old female with history of Crohn s disease. I have had this awful itching, burning rash in between my buttcheeks for the past year-- it comes and goes. I just recently noticed a change in appearance. there is an elevated area on the skin-- a thickening and it is red. It blanches when I press on it. I am worried that I have skin cancer/ or a melanoma growth that I have been avoiding. I have tried nystatin ointment, antifungal creams, the works. I dont know what else to do. I am just scared about the change/thickening in the skin. There are a few patches on inside of buttcheeks and i looked with a mirror and there is an crack near by rectum. I really wish i could get a biopsy like now! Your input is greatly appreciated!!