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Diabetic Patient With Chronic Kidney Disease Can Take Saxagliptin & Linagliptin Salts?
Sir my father is diabetic +CKD patient(9yrs &2yrs respectively)now our endocrinologist have started saxagliptin & Linagliptin salts.sir these salts r not prescribed in USA due due their side effects & so why prescribed in India.should he take this salt???
Sat, 7 Jun 2014
Thanks for your query. Both the drugs you mentioned are relatively safer in kidney disease as compared with metformin and some other anti diabetic medications. Coming to the point, saxagliptin still needs dose reduction in kidney disease if GFR is below 50 but linagliptin is not a problem at all as it is not excreted via kidney. So, linagliptin in general is the safest one when one consideres the dosing of these drugs in patient with chronic kidney disease.
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