I ve taken Lamictal for 20 years. Ånd lamotrigine for approximately 3 years for left temporal lobe partial complex epilepsy. Works quite well, but I am now feeling a lot of arthritic or neuropathy pain. I have a seizure every month or 2 ; ddon t always lose consciousness. My big question is what is the cumulative effect of Lamitcal. - lamotrigine after 22 years of use. Why do I have so much pain? Mood good, weight is good. Thanx! Based on what I ve read at this web site there is a huge number of reactions to using lamotrigine - maybe some generics are better - consistent than others. Maybe all of us users should be asked to rate the various sources..