re: GABBAPENTIN, I am COPD/Emphysema diagnosed. I am on 5 litre O2. I have been taking gabapentin for quite some time! I am beginning to experience more complicated side effects ... increased depression, mood changes, TROUBLE BREATHING, back ache, constipa/diary, DRY MOUTH and nose, trouble breathing, throat irritation, weight gain. Am anxious to heart reactions to today s headlines about opioid connection.