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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Letrozole Delay Periods?

I am a 31 yr old.have tried toconcieve fr 11/2yrs with no success .hsg showed right fimbrial adhesions.my husbands sperm analysis was ok.my ultrasound was gud.iv been on letrozole 2.5-5mg for 3mths.now my periods are late again.pt test was negative. 1.does letrozole delay menses ? 2.what should i now do? 3.how longer should i wait for my periods yet my back and lower abdomen hurt?
Thu, 15 Oct 2015
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General & Family Physician,  's  Response
Hi,
Thanks for posting in HCM.
I understand your concern.
Letrozole is an oral non-steroidal 'aromatase inhibitor', which is used for the treatment of hormonal-responsive breast cancer after surgery. It is administered to treat local or metastatic breast cancer that is hormone receptor positive.
Letrozole is also used for ovarian stimulation and is preferred by some doctors to Clomifene as it has lesser side effects and lesser incidence of multiple gestation.
Common side effects are sweating, hot flashes, joint pain and fatigue.
It is not known to cause delay in periods.
Hence, you need to get your serum FSH and LH hormonal levels along with thyroid profile checked to know what could be the cause for the delay.
Kindly consult Gynecologist for appropriate management.
Hope the information provided would be helpful.
All the best.
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Does Letrozole Delay Periods?

Hi, Thanks for posting in HCM. I understand your concern. Letrozole is an oral non-steroidal aromatase inhibitor , which is used for the treatment of hormonal-responsive breast cancer after surgery. It is administered to treat local or metastatic breast cancer that is hormone receptor positive. Letrozole is also used for ovarian stimulation and is preferred by some doctors to Clomifene as it has lesser side effects and lesser incidence of multiple gestation. Common side effects are sweating, hot flashes, joint pain and fatigue. It is not known to cause delay in periods. Hence, you need to get your serum FSH and LH hormonal levels along with thyroid profile checked to know what could be the cause for the delay. Kindly consult Gynecologist for appropriate management. Hope the information provided would be helpful. All the best.