Hi, Primolut N (norethisterone) is a synthetic progestogen hormone commonly used to regulate menstrual cycles and treat various gynecological conditions. It is not recommended to use Primolut N during pregnancy, particularly during the first trimester, unless specifically prescribed by a healthcare professional for a compelling medical reason. The use of Primolut N during pregnancy has been associated with an increased risk of fetal abnormalities, particularly when taken during the first trimester. Studies have suggested a potential link between the use of progestogens similar to Primolut N and an increased risk of genital abnormalities in male fetuses. If you suspect or confirm pregnancy while taking Primolut N, inform your healthcare provider immediately. They will assess your specific situation, weigh the potential risks and benefits, and provide appropriate guidance and alternative treatment options. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Muhammad Umer Farooq, General & Family Physician