Could Bromelain 240 GDU daily be the cause of my muscle cramps? My legs cramp worse at night but my arms, hands, knees, ribs, shoulder etc. cramp on exertion. My doctor is mystified after looking at numerous blood tests with normal results. I had a parathyroid removed a year ago when I started experiencing these horrible cramps. However, the blood tests show my thyroid to be functioning properly. I drink loads of water but find potassium and calcium to exacerbate the cramps. I am on an iron supplement for slight anemia and my creatinine is slightly elevated and eGFR slightly low. Help!