I have RA, taking methotrexate 0,8 weekly, also prednisone 2.5 daily. I also take tramadol prn for pain. I have profuse hot flashes whenever I do the least amount of activity, all morning long after showering, night sweats. I cannot get my rheumatologist to understand my deep discomfort all the time because of this. My thermostat is out of whack and has been for several years because of this. I am 61, now on disability and had breast cancer 9 years ago. Ever since I feel like my body has attacked me and not one day goes by where I feel normal anymore. Can one of these or all of these three drugs be causing this side effect? Any suggestions?Thank you for this service.Nancy