Hello bab, Welcome here on hcm. Unfortunately there is no cure for Hailey-Hailey disease. Treatment is aimed at reducing symptoms and preventing flares. Avoiding trigger factors such as sunburn, sweating and friction helps to control the disease. Wear absorbant pads in underwear Corticosteroid (cortisone) creams are effective in treating lesions and preventing exacerbations. Combination corticosteroid/ antibiotic creams are helpful, as treating the secondary infection is important. Prolonged courses of oral antibiotics such as tetracycline may be useful. Benzoyl peroxide is another useful antibacterial cream. Calcipotriol (Daivonex) cream is useful in some patients. If herpes virus infection is a recurrent problem oral antivirals such as aciclovir may be useful. A number of other oral medications (retinoids, ciclosporin, dapsone, and methotrexate) have been reported in single cases as partially effective, but large trials have not been performed. Wet compresses to dry up oozing patches Botulinum toxin to reduce sweating Phototherapy (ultraviolet light) has also been used. Photodynamic therapy has had varying success. Lasers have been reported to be useful in one study, vaporising the affected skin. In severe cases surgery can be performed to remove the affected skin. Skin grafts are usually necessary to repair the wounds. Thanks