Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties
159 Doctors Online

By proceeding, I accept the Terms and Conditions

Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

HCM Blog Instant Access to Doctors
HCM BlogQuestions Answered
HCM Blog Satisfaction

Have Bruise On The Thighs. Positive ANA. Have Muscle Pain, Fatigue, Blood In Urine. Positive For MTHFR. Bruise Impact Of MTHFR?

I have noticed unexplained bruising on my thighs (currently a total of 5 bruises). I have tested with a positive ANA (low positive) and have suffered from muscle pain and fatigue for the past 5 years, with no firm diagnosis. I also have had unexplained blood in my urine, but have had a full work up on my bladder (CT and cystoscopy), with no material findings (my mother also has this). A full CBC run just a few months ago was normal, except for the ANA. I have also tested postive for the Smith antibody and am positive for MTHFR. Is this bruising possibly related to an auto immune condition? Does the MTHFR have an impact? I am not on any medication, but do take a B12 and folic acid daily. I also took a very small dosage for predisone about 4 weeks ago, to help relieve inflammation from a back injury (twisted too much in yoga). Not sure if the predisone could cause bruising so much later?
Fri, 21 Jun 2013
Report Abuse
Pediatrician 's  Response
hello.thanks for using healthcaremagic.auto immune condition can cause bruising by platelet destruction.
but since you had one episode of blood in urine,i will recommend you to consult hematologist.. he may advice you to go for complete coagulation assay..since you are positive for MTHFR you should take active form of folic acid like l-methyl folate.it is less likely that steroid causes bruising so lately...hope i have answered your querries satisfactorily..have a nice day ahead..
I find this answer helpful

Note: Hope the answers resolves your concerns, however for further guidance of skin related queries consult our Dermatologist.Click here to book a consultation
Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer. For a more detailed, immediate answer, try our premium service [Sample answer]
Share on
 

Recent questions on Cystoscopy


Loading Online Doctors....
Have Bruise On The Thighs. Positive ANA. Have Muscle Pain, Fatigue, Blood In Urine. Positive For MTHFR. Bruise Impact Of MTHFR?

hello.thanks for using healthcaremagic.auto immune condition can cause bruising by platelet destruction. but since you had one episode of blood in urine,i will recommend you to consult hematologist.. he may advice you to go for complete coagulation assay..since you are positive for MTHFR you should take active form of folic acid like l-methyl folate.it is less likely that steroid causes bruising so lately...hope i have answered your querries satisfactorily..have a nice day ahead..