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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Have Central Serous Retinopathy. Taken Avastin For Impaired Vision. Need Expert

I am a 62 year old woman who was diagnosed 10 years ago with central serous retinopathy in my right eye. The problem appeared to resolve on its own in weeks. Two months ago, I noticed rather suddenly that the central vision in my right eye was severely impaired. After a series of tests, my ophthomologist told me that I had developed a rare CSR condition, a choroidal neovascular membrane, for which he injected me with Avastin. . He admitted that in all his years as a retinal specialist, he had never before seen a presentation such as mine. I wondered if you can help me locate someone with expertise in this condition, to offer additional guidance vis a vis treatment options. Many thanks.
Tue, 9 Jul 2013
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General & Family Physician 's  Response
Hello,
I am really sorry to read about your vision loss in the right eye. Here are a few pointers to help clarify what all is going on:

CSCR- central serous choroid retinopathy- is a type of condition which occurs in patients who are very type A personality (stressed, anxious etc.) in their mid 20s-30s (that does not mean that other individuals can not get it). This condition tends to resolve on it's own in a few weeks to months depending on the patient. When this resolves, it tend to leave a little mark behind. In many cases, if the behaviour/life style of the patient does not change then it tend to re-occur.

Choriodal neovascular membrane (CNVM) - occurs in many condition: uncontrolled diabetes, vascular diseases, age-related macular degeneration, best's disease etc. This happens when the innermost layer of the a membrane called Bruch's Membrane (BM), has a break. BM is barrier between retina and the choroid. Choroid contains pool of blood which helps nourish the retina with nutrients and oxygen. When there is break in BM, the fluid that is in choroid starts to seep though the retina causing hypoxia to the tissue around it leading to a neovascular membrane. To treat the neovascular membrane, ophthalmologists will inject medication whose main purpose is to have that neovascular membrane retreat with causing minimal harm. The injection contains something called anti-vascular epithelial growth factor. It is really important that this membrane heals in order for some vision to come back.

Hope this helps.
Dr. Jay Patel
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Have Central Serous Retinopathy. Taken Avastin For Impaired Vision. Need Expert

Hello, I am really sorry to read about your vision loss in the right eye. Here are a few pointers to help clarify what all is going on: CSCR- central serous choroid retinopathy- is a type of condition which occurs in patients who are very type A personality (stressed, anxious etc.) in their mid 20s-30s (that does not mean that other individuals can not get it). This condition tends to resolve on it s own in a few weeks to months depending on the patient. When this resolves, it tend to leave a little mark behind. In many cases, if the behaviour/life style of the patient does not change then it tend to re-occur. Choriodal neovascular membrane (CNVM) - occurs in many condition: uncontrolled diabetes, vascular diseases, age-related macular degeneration, best s disease etc. This happens when the innermost layer of the a membrane called Bruch s Membrane (BM), has a break. BM is barrier between retina and the choroid. Choroid contains pool of blood which helps nourish the retina with nutrients and oxygen. When there is break in BM, the fluid that is in choroid starts to seep though the retina causing hypoxia to the tissue around it leading to a neovascular membrane. To treat the neovascular membrane, ophthalmologists will inject medication whose main purpose is to have that neovascular membrane retreat with causing minimal harm. The injection contains something called anti-vascular epithelial growth factor. It is really important that this membrane heals in order for some vision to come back. Hope this helps. Dr. Jay Patel