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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Having Post Natal Depression. Was Taking Venlafaxine Previously. Thought It Brought Down The Immune System. Suggestions?

My Daughter is 40 years old ant has had post natal and depression for the last 20 odd years off and on. She had been taking Venlafaxine for 7 months last year and the last two months she weaned herself off them and now feels really bad. She thinks it lowered her immune system because she caught a nasty virus. I told her it doesn t lower your immune system she just caught a virus like we all do this time of the year. She also said one of the side affects was heavy , can this be true?
Sat, 30 Mar 2013
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Psychiatrist 's  Response
Hi there, thanks for asking. Venlafaxine does not weaken the immune system. It may have some side effects which are mostly manageable with lowering the dose or adding another medication. It is a good medication for treating depression as well. If she feels that she is not comfortable with this medication, she can ask her doctor to give her another medication. Post pregnancy depression is a serious disorder and should be treated completely. If the medication is discontinued by doctor, she will remain well after. Best wishes.
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Psychiatrist Dr. Sundar Gnanavel's  Response
Hello............
Thanks for your query. As you rightly mentioned, venlafaxine, a SNRI group of antidepressant is unlikely to have led to a compromise of her immune system and viral infection. I would suggest that you consult a psychiatrist and restart her on venlafaxine or a different antidepressant considering her history of postnatal depression.
It is better not to stop psychotropic medication without a discussion with a psychiatrist as it may lead to relapse/rebound of symptoms. Wish her good health.
Regards
Dr Sundar
Psychiatrist
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Having Post Natal Depression. Was Taking Venlafaxine Previously. Thought It Brought Down The Immune System. Suggestions?

Hi there, thanks for asking. Venlafaxine does not weaken the immune system. It may have some side effects which are mostly manageable with lowering the dose or adding another medication. It is a good medication for treating depression as well. If she feels that she is not comfortable with this medication, she can ask her doctor to give her another medication. Post pregnancy depression is a serious disorder and should be treated completely. If the medication is discontinued by doctor, she will remain well after. Best wishes.