I have spinal stenosis, lumbar & cervical radiculopathies, herniated disc, polyneuropathy, carpel tunnel syndrome, arthritis in every level of the spine, a fractured thoracic, severe glenohumeral arthritis in right arm, severe pain in left arm and cannot have a bowel movement. Have tried prunes, miralax, drinking tons of water, unprocessed wheat, exercise walking a mile per day, and yet Fort Know would be easier to rob than trying to have a bowel movement. Sometimes when I do have a bowel movement, feces comes out after I think I am done and my clothes are ruined. What a mess!