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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How Can Elevated CPK And SGPT Levels Be Treated?

For the last six months i was on tri-weekly Fenofibrate 160 and Folvite 5 mg once aday.My CpK was 329 and SGPT 116. Then all earlier medicines were stopped. For the last one month I was on Ursodeoxycholic acid 300 twice a day. I walked every morning for 45 minutes. Now my CPK is 353 and SGPT is 171. Please suggest what to do.
Thu, 26 Jul 2018
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General & Family Physician,  's  Response
Hello welcome to 'Ask A Doctor' service.
I have reviewed your query and here is my advise.

Fenofibrate in few patient can lead muscle breakdown. Cpk is released in blood when muscle injury is present. So this drug need to be stopped. Your sgpt elevated Hence liver injury also present. Ursodeoxycholic acid is advisable to continue. Avoid high fatty foods. Sugar cane juice and apple juice can be taken. Investigate with viral marker study and provide history about alcohol intake as well if present. USG abdomen scan should be done.
I suggest you to consult physician for examination.

Hope I have answered your question.
Let me know if I can assist you further.
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How Can Elevated CPK And SGPT Levels Be Treated?

Hello welcome to Ask A Doctor service. I have reviewed your query and here is my advise. Fenofibrate in few patient can lead muscle breakdown. Cpk is released in blood when muscle injury is present. So this drug need to be stopped. Your sgpt elevated Hence liver injury also present. Ursodeoxycholic acid is advisable to continue. Avoid high fatty foods. Sugar cane juice and apple juice can be taken. Investigate with viral marker study and provide history about alcohol intake as well if present. USG abdomen scan should be done. I suggest you to consult physician for examination. Hope I have answered your question. Let me know if I can assist you further.