Hello there I have read through your question and understand your concern. Hydrochlorothiazide is a diuretic which may be worsening her macular degeneration. It is advisable to put her on a different antihypertensive like a calcium channel blocker like amlodipine which is also an effective option. You can discuss this with her physician. With that salt restriction and low cholesterol diet should be followed. I hope that answers your question. If you have any further questions please feel free to write. Thank you for choosing healthcare magic.