Hi, Psoriasis is a chronic skin disease that speeds up the life cycle of skin cells. It causes cells to build up rapidly on the surface of the skin. The extra skin cells form scales and red patches that are itchy and sometimes painful. The cause of psoriasis isn t fully understood, but it s thought to be related to an immune system problem. To answer your question, I can say that: There is no permanent cure for psoriasis, but you can manage symptoms. Lifestyle measures, such as moisturizing, quitting smoking, managing stress and exposing your skin to controlled amounts of natural sunlight(phototherapy) may be helpful. At the other side topical and sistemic corticosteroids, topical Vit D analogues, salicylic acid and retinoids are used to manage the exacerbation of the disease (like in your wife s case). I suggest discussing with your wife s treating doctor about the best alternatives for treatment in your wife s specific case. Hope I have answered your query. Let me know if I can assist you further.