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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How Effective Is Hydergine Compared To Other Medications To Fight Alzheimer's Disease?

Doctor, My dad is suffering from Alzheimer's Disease and he had been prescribed Hydergine. However it seems that the drug is no loner available in the market. Doctor, is the drug being marketed by the manufacturing company? Also, I want to understand the levels of efficacy of Hydergine vis-a-vis other drugs like Piracetam, mementine, rivastigmine and Donepezil. If it is efficacious, I may contact the manufacturer to send me the medicine. Also doctor what are the differerent dosage forms in which the drug is available because my dad is not able to swallow medicines. Also doctor please tell me if the foresaid drugs are more efficacious in the treatment in what manner they are more efficacious in terms of duration of treatment, therapeutic action and efficacy. My curiosity is higher relating to the Alzheimer's Disease because I am myself a medical student doing my MBBS. Thank you doctor
Mon, 13 Oct 2014
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Neurologist 's  Response
If it's a correct diagnosis of Alzheimer's disease, than the best options are cholinesteraze-inhibitors drugs (denepezil or rivastigmine or galantamine) and memantine, either alone or in combination, depending on the stage of the disease. These are the only ones approved for Alzheimer's and the treatment is continued indeterminately unless there are side effects. They do not cure or stop the disease, only slow down it's progression.
Drugs like piracetam or hydergine, are not specific to Alzheimer's, they are used as general enhancers of higher mental functions, used to be given for Alzheimer as well, but their effect hasn't really been proven by clinical studies and is modest at best.
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How Effective Is Hydergine Compared To Other Medications To Fight Alzheimer's Disease?

If it s a correct diagnosis of Alzheimer s disease, than the best options are cholinesteraze-inhibitors drugs (denepezil or rivastigmine or galantamine) and memantine, either alone or in combination, depending on the stage of the disease. These are the only ones approved for Alzheimer s and the treatment is continued indeterminately unless there are side effects. They do not cure or stop the disease, only slow down it s progression. Drugs like piracetam or hydergine, are not specific to Alzheimer s, they are used as general enhancers of higher mental functions, used to be given for Alzheimer as well, but their effect hasn t really been proven by clinical studies and is modest at best.