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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How Long Will Prednisone Remain In The System?

i completed taking prednisone on Christmas day and had been on it for 21 days total,my anxiety,mood changes ,but most of all,insomnia,is continuing. i also have been taking some oxycodone for the last week.was wondering about how long will this gtake to get out of my system or for these side effects to end.
Thu, 28 Jan 2016
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Dentist 's  Response
Hi Welcome to HEALTHCARE MAGIC..

I have gone through your query and can understand your concern...
Prednisone has half life of 18 to 36 hours. It is converted into active form prednisolone in liver. After which it is excreted by kidneys. So a dose of prednisone will stay upto 10 days in body maximum.
As per the side effects taking prednisone, you are facing like anxiety,mood changes, insomnia should decrease in 2-3 days. These effects are short term effects only. They might be also related to intake of oxycodone, which is morphine derivative.

Refer to your physician
Hope this information helps
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How Long Will Prednisone Remain In The System?

Hi Welcome to HEALTHCARE MAGIC.. I have gone through your query and can understand your concern... Prednisone has half life of 18 to 36 hours. It is converted into active form prednisolone in liver. After which it is excreted by kidneys. So a dose of prednisone will stay upto 10 days in body maximum. As per the side effects taking prednisone, you are facing like anxiety,mood changes, insomnia should decrease in 2-3 days. These effects are short term effects only. They might be also related to intake of oxycodone, which is morphine derivative. Refer to your physician Hope this information helps