Hi. Thanks for posting query at HCM. Usually ALT or AST values higher than two times the upper normal limit , is considered abnormal ( in some countries, ALT or AST values of more than 100 are considered abnormal). Value of AST or ALT greater than 85 or above maybe investigated further. Alcohol ingestion and obesity are common causes of fatty liver disease. however, you may have tests to rule out Hepatitis B and C infection. you have high cholestrol advice : - abstinence from Alcohol - LOW fat diet should be followed, -AVOID junk food and beverages - decreased oil consumption (oily food) - NO red meat - green vegetables should be ingested daily - use lemon juice (lemonade) once in a day - recheck liver enzymes and lipid profile after 3 months if cholesterol is still high, you have to use medication to combat the high cholesterol. do not take any medication unnecessarily. consult treating physician if you still need b vitamins and/or zoloft. prevention is better than cure and you should follow strict diet to bring the enzyme values back to normal. hope to answer your concern. wish you good health. regards, Dr Tayyab Malik