Nexito is escitalopram by composition. It is a Selective Serotonin Re-uptake Inhibitor [SSRI]. It is an excellent and very safe antidepressant, also have efficacy in various neurotic disorder like Generalised Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), Panic Disorder, Agoraphobia, OCD etc.. Its side effects are very mild. It does not have any abuse liabilities, does not produces any dependences or tolerance. Its withdrawal syndrome are very mild, in fact does not produces any distressing symptoms on gradual discontinuation. Most likely you have been prescribed Nexito for your Anxio-depressive disorder. You should not be worried about the long term intake of escitalopram in 5 or 10 mg doses. Although book says a depressed person should take SSRI for at least 2 years after the onset of depressive symptoms for the first time, but practically I have seen many patients taking SSRI for many years without any problems. As you said , you face rebound effect upon discontinuation of Nexito, it does not mean that the drug is bad, in fact your disease is bad. It relapses when you discontinue your medication even on gradual tapering of dose. In my opinion, you should take Nexito in 5 mg doses and to remain in close follow up with your treating psychiatrist until he/she decides to taper it further or discontinue it totally. You should not be worried of its long term intake and should not try yourself to discontinue it on your own. Thank You... (Viewer rating for my answer is my consultation fee here )