I had the exact same thing happen after the first 48 hours on HCG! I stopped it immediately and took DIM, and extra Vitamin E. It took a week before I could stop the DIM and not have pain. My breasts had also swelled up. I had my ovaries removed years ago, so it was not due to menstral cycles. I did have breast pain when my replacement testosterone levels were too high years ago, but never like I did on the HCG. The HCG was awful, the pain woke me up from my sleep! It has also greatly increased my husbands testicles! That worries me, but he has continued with the drops. His excess weight problems are greater than the swelling, I guess. Lugal s iodine drops are great for helping with breast lumps, along with Vitamin E and DIM for ladies with genetic tendencies toward Breast C.