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IHC Report Showed CD117 Positive, CD 34 Focal Positive, Ki-67 Positive 1%. Diagnosed GIST. History Of Removal Of Tumor From Small Intestine. Right Diagnose?
Hi, I am 58 years old male. Recently i removed tumor from small intestine with a size of 6x5x4 cm.
My IHC report was, CD117 positive and CD34 with focal positive, while SMA is negative and ki-67 is positive with 1%.
Based on these data our physician diagnos as it was GIST and start imatinib. My query is that is it sufficient data to diagnos for GIST and as per the data how long I have to take imatinib.
My IHC report was, CD117 positive and CD34 with focal positive, while SMA is negative and ki-67 is positive with 1%.
Based on these data our physician diagnos as it was GIST and start imatinib. My query is that is it sufficient data to diagnos for GIST and as per the data how long I have to take imatinib.
Fri, 7 Jun 2013
Hi and welcome to HCM. Thank you for your query.
It is never 100%,but it is enough for right diagnosis. Also GIST can be easily recognized by morphological characteristic which can be seen during the surgery and by clear borders and non-infiltration of surrounding tissue.
If imatinib is used just for prevention of recidive then it should be used only short time. If there is still evidence of tumor then it has to be taken for 6m-1 year. Wish you good health. Regards
It is never 100%,but it is enough for right diagnosis. Also GIST can be easily recognized by morphological characteristic which can be seen during the surgery and by clear borders and non-infiltration of surrounding tissue.
If imatinib is used just for prevention of recidive then it should be used only short time. If there is still evidence of tumor then it has to be taken for 6m-1 year. Wish you good health. Regards
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