** 1. ANA [anti nuclear antibody] is done to see whether there is an autoimmune attack going inside the body where the antibodies are attacking a protein in the nucleus and most important cause of positive ANA is SLE [systemic lupus erythematous] but there are certain other rheumatic conditions where one may find positive ANA [check with a rheumatologist] thus one has to exclude them also before starting for any treatment, these are: . Rheumatoid Arthritis . Systemic Sclerosis [Scleroderma] . Mixed Connective Disease [MCD} . High values are considered as ongoing active infection inside the bodies thus have a Rheumatologist examination and initially steroids are often used to suppress the body s immune system thus go for prednisolone, hydrocortisone.