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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is ATT Safe During Pregnancy?

hi i m 12 weeks pregnant and have been diagnosed with tubercular lymphadenitis (cervical).. jst wanna knw whether ATT is safe during pregnancy,whether it will affect the foetus in any sense??is there any risk of congenital or any other problem to the baby??
Mon, 21 Sep 2015
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General & Family Physician,  's  Response
Hi & Welcome.

I appreciate your concern for the safety of Anti TB medications during pregnancy.

The standard treatment of TB involves 2 phases of treatment:

An initial intensive phase (2-3 months) followed by a continuation phase (4-6 months). 4 drugs (Isoniazide, Rifampicin, Pyrazinamide, Ethambutol or Streptomycine ) are given in the initial phase followed by 2 drugs (Isoniazide and Rifampicin) in the continuation phase.

During pregnancy the following 2 drugs are not safe:

1. Streptomycin (WHICH CAN CAUSE CONGENITAL/NEONATAL DEAFNESS)
2. Pyrazinamide (WHICH CAN CAUSE SPINA BIFIDA IN THE NEW BORN)

Hence in view of their possible harmful effects on the growing baby (fetus), these 2 drugs should not be taken.

Hope the suggestion is useful

A feed back is appreciated.

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Is ATT Safe During Pregnancy?

Hi & Welcome. I appreciate your concern for the safety of Anti TB medications during pregnancy. The standard treatment of TB involves 2 phases of treatment: An initial intensive phase (2-3 months) followed by a continuation phase (4-6 months). 4 drugs (Isoniazide, Rifampicin, Pyrazinamide, Ethambutol or Streptomycine ) are given in the initial phase followed by 2 drugs (Isoniazide and Rifampicin) in the continuation phase. During pregnancy the following 2 drugs are not safe: 1. Streptomycin (WHICH CAN CAUSE CONGENITAL/NEONATAL DEAFNESS) 2. Pyrazinamide (WHICH CAN CAUSE SPINA BIFIDA IN THE NEW BORN) Hence in view of their possible harmful effects on the growing baby (fetus), these 2 drugs should not be taken. Hope the suggestion is useful A feed back is appreciated.