Hello Thank You for contacting HCM. Yes duphaston is a wonderful formulation as it has dydrogesterone which is progesterone and thus helps in supplementing placental function and thus preventing preterm labor. It is also the best tolerated progesterone out of all other formulations. If it is making you very nauseated then you can take it with meals and avoid taking large amounts of liquids along. If your doctor has prescribed then you must take. Take complete bed rest. take balanced and healthy diet. Continue taking your supplements. Avoid exertion or strenuous work. Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us. Wishing you good health.