I have been on Effexor, not XR, for a couple of months. I am now at 150mg. I have gained 15lbs in one month. I thought Effexor s side effect was more common weight loss. I eat a high protein,low fat,low carb diet. Recently I have had problems with stomach bloating and distension. Other meds I am on are Linzess390mg, suboxone 16mg, tapering off valium - now at 17.5mg, and Prempro .0625/2.5mg - I am in menopause. I don t eat Gluten, occasionally have candy, no bread,pasta,or other carbs. I drink protein shakes and protein bars, all are soy/whey protein and have no sugar,gluten,lactose, 2 grams fat,and little to 0 carbs. why is my stomach so huge? I am also concerned about Effexors effects of increasing cholesterol and triglycerides.