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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is It Advisable To Take Duphaston To Conceive In A 42 Yr Old Female With Low AMH?

Hi, I am 42yrs old & have very low AMH, but my cycles are regular. Trying to concieve for last 2years, but all in vain. Tired of taking medicines after medicines. It looks like its endless, Started feeling that I will never ever concieve. One of my friend suggested me Duphaston, is it advisable & safe to take it.
Thu, 30 Jan 2014
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OBGYN,  's  Response
Hello
Thanks for writing to us with your health concern.
AMH reflects the ovarian reserve.
See basically in males, spermatogenesis is a dynamic process.
It continues well into the seventies or eighties.
However, in a girl child, when she is born, there is a limited number of eggs in the ovaries.
With each menstrual cycle, the egg follicles get used up.
In the 40s and as menopause approaches, the eggs decline drastically.
A low AMH indicates that your ovarian resrve is quite low.
With a low AMH, chances of spontaneous conception are not very good.
You should consult a fertility specialist, and go for IVF ( in vitro fertilization ) - that would be your best shot at conception attempts.
Also, Duphaston contains progesterone.
It is safe, but in NO WAY does it improve your ovarian reserve.
Taking DHEA supplements will help marginally.
All the best
Take care.
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Is It Advisable To Take Duphaston To Conceive In A 42 Yr Old Female With Low AMH?

Hello Thanks for writing to us with your health concern. AMH reflects the ovarian reserve. See basically in males, spermatogenesis is a dynamic process. It continues well into the seventies or eighties. However, in a girl child, when she is born, there is a limited number of eggs in the ovaries. With each menstrual cycle, the egg follicles get used up. In the 40s and as menopause approaches, the eggs decline drastically. A low AMH indicates that your ovarian resrve is quite low. With a low AMH, chances of spontaneous conception are not very good. You should consult a fertility specialist, and go for IVF ( in vitro fertilization ) - that would be your best shot at conception attempts. Also, Duphaston contains progesterone. It is safe, but in NO WAY does it improve your ovarian reserve. Taking DHEA supplements will help marginally. All the best Take care.