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Dr. Andrew Rynne

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Is It Safe To Have Soy Isoflavones Vitamins Along With Metformin To Get Pregnant?

I have been taking metformin for 2 months going on 3 months for pcos. Im trying to conceive. I have heard of some women taking soy isoflavones vitamins with metformin and it helping them get pregnant. Is this true and is it safe for me to try this? I have been trying to concieve for 5 years now.
Mon, 6 Feb 2017
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OBGYN,  's  Response
Hallow Dear,

In Polycystic Ovarian syndrome, the main disorders are infertility due to failure to release eggs (ovulation) as a result of dysfunction in reproductory hormones, raised insulin levels and raised androgens.

Metformin helps bring down the levels of Insulin. It acts as a good adjuvant to the medicines used for induction of ovulation. The success of only Metformin for the treatment of anovulatory infertility is questionable. According to some scientists, Myo inositol brings down the levels of Insulin as well as androgens and hence is more effective in the treatment of infertility due to PCOS.

For induction of ovulation, Clomiphene citrate may be tried for 6 cycles (along with Metformin or Myo inositol). If it fails, HMG/hCG combination may be tried.

PCOS is characterised by obesity. Please calculate your BMI. You should maintain your BMI between 18 and 23.9 by reducing weight by apt diet and exercises.

Soy isoflavones are supposed to improve general health as well as the quality of the eggs, increasing the possibility of successful pregnancy. They are quite safe in your treatment.

I hope this will help you to seek for a comprehensive management of PCOS. Please report to your Infertility consultant.

Dr. Nishikant Shrotri
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Is It Safe To Have Soy Isoflavones Vitamins Along With Metformin To Get Pregnant?

Hallow Dear, In Polycystic Ovarian syndrome, the main disorders are infertility due to failure to release eggs (ovulation) as a result of dysfunction in reproductory hormones, raised insulin levels and raised androgens. Metformin helps bring down the levels of Insulin. It acts as a good adjuvant to the medicines used for induction of ovulation. The success of only Metformin for the treatment of anovulatory infertility is questionable. According to some scientists, Myo inositol brings down the levels of Insulin as well as androgens and hence is more effective in the treatment of infertility due to PCOS. For induction of ovulation, Clomiphene citrate may be tried for 6 cycles (along with Metformin or Myo inositol). If it fails, HMG/hCG combination may be tried. PCOS is characterised by obesity. Please calculate your BMI. You should maintain your BMI between 18 and 23.9 by reducing weight by apt diet and exercises. Soy isoflavones are supposed to improve general health as well as the quality of the eggs, increasing the possibility of successful pregnancy. They are quite safe in your treatment. I hope this will help you to seek for a comprehensive management of PCOS. Please report to your Infertility consultant. Dr. Nishikant Shrotri