Hi, thanks for writing to HCM.
Using TIZANIDINE together with NEURONTIN (gabapentin) and CYMBALTA (duloxetine) may increase side effects such as drowsiness, dizziness,
lightheadedness, difficulty concentrating, and impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with these medications.
Using TIZANIDINE together with SUBOXONE (
buprenorphine) can lead to serious side effects such as
respiratory distress or even coma, depending upon the dose concentrations.
Tizanidine is a short acting
muscle relaxant used to treat muscle spasticity thereby temporarily relaxing the
muscle tone. As with any other drug, tizanidine also produces few systemic adverse reactions.
Consult your treating doctor and discuss the issues.
Hope this information is helpful. Good day