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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is It Safe To Take Heptral,evion,glycomet And Zyloric For Fatty Liver?

hi

I have got LFT done in which ALT and AST , GGT and are almost triple the normal range and Uric acid test is also double . Also whole abdomen ultra sound reflected fatty liver -II and rest everything came normal including liver shape and size.

Gastro prescribed :-
Heptral 400 mg twice daily
Evion Vit E 400 IU daily
Glycomet 500mg twice daily(weight loss)
Zyloric 100mg 3 times daily(for high uric acid)

Is it safe to take all medicine for fatty liver -ii or do i need to change or add any other medicine in it ?

Regards
Mike







Wed, 30 Dec 2015
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General & Family Physician 's  Response
Hi.
I went through your concerns regarding your condition of fatty liver and a high ALT level.
It's a condition in which triglycerides are deposited in the liver. In 20% of patients which causes inflammation in the liver and high ALT level, the condition is called NASH.
NASH is more dangerous than fatty liver. 20% of patients with NASH will develop cirrhosis of liver.
Your condition is NASH. It is a control able condition. The first line management is achieving weight loss by life style n dietary modification. You should avoid junk foods, oily foods and sweets.
you should continue combination of capsule ursodeoxycholic acid 250-300 mg once a day and capsule Vitamin E 200-400 mg once a day.
This combination has shown promising effect in clinical trials.
Ursodeoxycholic acid is a safe drug. It has narrow spectrum of side effects like nausea, vomiting, diarrhea, headach, dizziness and dyspepsia. But most of patients tolerate it very well.
Clinical data has also shown proven role of metformin which you are already taking.
You have been prescribed appropriate treatment for your condition (NASH). You should continue this treatment regimen and try to lose weight.
you should continue Zyloric which is for your high uric acid. But it has no definite role in fatty liver/NASH.
I wish you good luck.
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Is It Safe To Take Heptral,evion,glycomet And Zyloric For Fatty Liver?

Hi. I went through your concerns regarding your condition of fatty liver and a high ALT level. It s a condition in which triglycerides are deposited in the liver. In 20% of patients which causes inflammation in the liver and high ALT level, the condition is called NASH. NASH is more dangerous than fatty liver. 20% of patients with NASH will develop cirrhosis of liver. Your condition is NASH. It is a control able condition. The first line management is achieving weight loss by life style n dietary modification. You should avoid junk foods, oily foods and sweets. you should continue combination of capsule ursodeoxycholic acid 250-300 mg once a day and capsule Vitamin E 200-400 mg once a day. This combination has shown promising effect in clinical trials. Ursodeoxycholic acid is a safe drug. It has narrow spectrum of side effects like nausea, vomiting, diarrhea, headach, dizziness and dyspepsia. But most of patients tolerate it very well. Clinical data has also shown proven role of metformin which you are already taking. You have been prescribed appropriate treatment for your condition (NASH). You should continue this treatment regimen and try to lose weight. you should continue Zyloric which is for your high uric acid. But it has no definite role in fatty liver/NASH. I wish you good luck.