An 8 year old patient (inborn hemiplegia, history of seizures, treated with oxcarbazepine (not successful), valproate, levetiracetam, clobazam, then topimarate, medication paused for more than six month, no relapse so far) suffers from severe itching after surgical therapy (4 days ago) of a burn(10% of the skin, split-skin autograft, normal healing so far). Uncommon tolerance to narcotics, probably due to antiepileptic medication in the past, arrested attention, so that otherwise indicated sedatives (I thought of lorazepam) are advised against. Is there a considerable seizure risk when applying loratidine?