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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Knee Replacement. Have Nausea, Hives, Neurological Side Effects. Is It Due To Clindamycin?

Could just 300mg Clindamycin taken prior to dental work necessary d/t bilateral knee replacements. I didn t realize it was same as Cleocin and previously I had giant hives after taking Cleocin. I am on Coumadin. I developed nausea, neurological side effects, and a rash that started with small red bumps which spread out like hives, but barely itched, then turned purple and then a grayish color. Need to differentiate between Coumadin purpera and reaction to the Clindamycin. The rash did not start for about six days. My doctor ordered a CBC but no results back yet. (I did not know there was a charge. I m not able to pay Sorry)
Wed, 20 Mar 2013
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Dentist 's  Response
Hi,
Thank you for the query.
Yes, cleocin and clindamycin is the same drug and the side effects of these drugs present with nausea, itching, rash, heart burn and prolonged use may result in oral thrush.It appears to be a clindamycin reaction than a coumadin purpura which is a bleeding disorder .
I would advise you to wait till you get CBC results and then consult your doctor.
Diagnosis can be made according to the reports soo discuss the treatment with your doctor.
Hope this information helps you.
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Dentist Dr. Anshumala Singh's  Response
Dear friend.

Thanks for sharing your concern.

It could be due to drug reaction or an allergic response.

In this case i would suggest you to visit a dermatologist and get your self examined for your allergic reactions.

meanwhile you can discontinue the drug.

also you can visit your dentist for changing your antibiotic.

Hope it helps.
thanks
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Dentist Dr. Naiem's  Response
u checkup ur allergy test and consult to dermatologist.............
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Knee Replacement. Have Nausea, Hives, Neurological Side Effects. Is It Due To Clindamycin?

Hi, Thank you for the query. Yes, cleocin and clindamycin is the same drug and the side effects of these drugs present with nausea, itching, rash, heart burn and prolonged use may result in oral thrush.It appears to be a clindamycin reaction than a coumadin purpura which is a bleeding disorder . I would advise you to wait till you get CBC results and then consult your doctor. Diagnosis can be made according to the reports soo discuss the treatment with your doctor. Hope this information helps you.