I have been on Celebrex for a long time (years). I am a 70 year old lady. In January, my Doctor doubled the dose from 100 mg once a day to 100mg twice a day. I have had arthritis since age 25. Doctor didn t say why so I ASSUMED my blood tests warranted the increase. I have Asthma , Had pneumonia February (2013). Had the flu three times since October, 2012. I have high BP and take med. with a fluid reducer which FR was discontinued. My thyroid med. was 0.088 but was reduced now to 0.075. I have Celiac disease . Also, some other problems.