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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Parkinson's Disease Under Control, Have Continuous Trembling In Hand, Taking High Dosage Of Syndopa. What Is The Cause?

my mother now aged 80 years was affected during 2005 by a stroke and suffering with parkinsons but however now almost under control by taking medicines regularly. Now I want to know is ,out of those medicines, one medicine syndopa 110mg is taking regularly dosage as one in morning and one in night. What i want to know is she is prescribed the syndopa 275 for 3 times as she is reporting the regular doctor that she is still having hand shivering . please advise on this overdosage
Fri, 19 Sep 2014
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General & Family Physician 's  Response
Hello,

Thank you for trusting HCM.

Parkinson current accepted treatment is dopamine replacement therapy, since in the basal ganglia in specifically substania nigra dopamine releasing neurons are degenerating in Parkinson disease which leads to the common symptoms of tremor rigidity and posture. with those medications there are 2 problems first stability level thats why they need to be taken at different times of the day, the other problem is when the disease progresses more is need to compensate for the loss of normal released dopamine from the brain. That is why your doctor increased the dose for your mother. stay well hope that helped explaining things for you.

Dr. Nazzal
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Parkinson's Disease Under Control, Have Continuous Trembling In Hand, Taking High Dosage Of Syndopa. What Is The Cause?

Hello, Thank you for trusting HCM. Parkinson current accepted treatment is dopamine replacement therapy, since in the basal ganglia in specifically substania nigra dopamine releasing neurons are degenerating in Parkinson disease which leads to the common symptoms of tremor rigidity and posture. with those medications there are 2 problems first stability level thats why they need to be taken at different times of the day, the other problem is when the disease progresses more is need to compensate for the loss of normal released dopamine from the brain. That is why your doctor increased the dose for your mother. stay well hope that helped explaining things for you. Dr. Nazzal