Perforated Ear Drum Medication

Ofloxacin Inoflox 4 drops 3 times a day for 1 week and Clotrimazole Canesten 4 drops 3 times a day for 3 weeks on a Perforated Ear Drum (Permanent Big Hole in my ear)? Is it ok to drop Ofloxacin Inoflox 3 mg/ml antibacterial OTIC SOLUTION ear drops, 4 drops 3 times a day for 1 week on a peroforated ear drum (a big hole in my ear drum)? and wait 5 minutes with head tilted and then let it drains out, then drop Bayer s Clotrimazole Canesten 1% solution Antifungal 4 drops 3 times a day but for 3 weeks also on a peroforated ear drum (a big hole in my ear drum) and wait for 5 minutes with my head tilted until letting it drains out? will this possibly damage my ear or is it ok ? -Dickson