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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Pernicious Anemia In Line With Intrinsic Factor. Had A Gastric Bypass Surgery. Is It Megaloblastic Anemia?

hi there, I'm in pharmacy school working on a Case Study and I am slightly confused. Our "patient" had a gastric bypass surgery. His current iron levels are higher than the normal range. His b12 though levels are low. Since pernicious anemia is in line with Intrinsic Factor, would this case be clarified as pernicious or simply megaloblastic anemia?
Thu, 3 Oct 2013
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General & Family Physician 's  Response
Hello,
In gastric by pass surgery,a major portion of stomach is bypassed which results in formation of just a pouch which acts like a funnel to transit your food.
This bypassed portion of stomach makes the intrinsic factor and since food doesn't go into that area,the person develops a VIT B12 deficiency.
In essential this condition is a megaloblastic anemia,since you are not deficient in intrinsic factor as present in pernicious anemia.
Thanks
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Pernicious Anemia In Line With Intrinsic Factor. Had A Gastric Bypass Surgery. Is It Megaloblastic Anemia?

Hello, In gastric by pass surgery,a major portion of stomach is bypassed which results in formation of just a pouch which acts like a funnel to transit your food. This bypassed portion of stomach makes the intrinsic factor and since food doesn t go into that area,the person develops a VIT B12 deficiency. In essential this condition is a megaloblastic anemia,since you are not deficient in intrinsic factor as present in pernicious anemia. Thanks