Hi Vishakha, Welcome to Healthcare Magic and thanks for your question... Hearing non-existent noises / voices (in medical terms known as hallucinations ) is indicative of psychosis , which is a particular type of psychiatric disorder. The current combination of medication which he is taking, already has an anti-psychotic medication i.e. Trizyne S (Trifluoperazine). In addition, he is also on a mood-stabilizing medication i.e. Divalproex. Though you have mentioned the diagnosis as depression , he is not on any anti-depressant medication currently. But remember, the word depression can often used in a non-specific manner by many people, and I m guessing that he may actually be suffering from a psychotic disorder . RIVOTRIL (I presume, not Revetriol ) is a sedative medication and is used for sleep disturbances and sometimes, to calm down the patient. My opinion is that if he is having psychotic symptoms, it is advisable to treat that specifically (probably by increasing the anti-psychotic medication), rather than merely keep giving him a sedative. Of course, this has to be done only on consultaion with a psychiatrist. I would suggest that if you are able to contact him over phone or see his colleague for a quick review, that would be a better idea. All the best. - Dr. Jonas Sundarakumar Consultant Psychiatrist