I began taking Eliquis on 3/3/14 for a clot in my right jugular vein. The clot was apparently caused because I had a brain operation on 1/15/14 for trigeminal neuralgia, a cranioectomy behind my right ear and then an MVD of the trigeminal nerve. The operation worked great and I felt fine from it almost immediately. The clot is another thing! Spent more than a week of intense pain and discomfort before they scanned my neck and found that it was from a clot and not an infected thyroid. I am still weaning off carbamazepine. I have begun feeling very weak and have had pains running down my arms and legs, and some difficulty in taking my daily walk. My doc said to just overcome it and keep walking. He estimates that I will be able to stop taking Eliquis within 3 months. My other meds are Synthroid, Vitamin D, carbamazepine, losartan and amlodipine (latter as necessary). The weakness is severe and I don t like it. What is your opinion as to what I should do?