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Should I Continue Taking Isotroin -10 When Acne Is Healing Or Change The Dose?
sir, i m 23 years male,i am suffering from nodular acne vulgaris since 18th september,,,i have shown it to doctor and she said it will take 4-5 months of course to treat it completely.she had started with a mild dose i.e 1 per day of isotroin-10 along with azilide and omnicortil,..and then after 10 days she increased it to 2 per day ..i want to ask if there is a need to consult again as my acne has started to heal now..should i continue with isotroin-10 2 tablets per day or should i increase the dose????
Thu, 24 Apr 2014
Hello and welcome to healthcaremagic
For severe acne OR for acne unresponsive to traditional anti-acne medications, Isotretinoin is the drug of choice. It the only drug which offers any chance of long term cure and after a full course of isotretinoin significant number of people never have a recurrence of there acne. However it should be given in the right dose and for the right duration.
Total Cumulative dose of Isotretinoin that should be taken is 120-140mg/kg.
For a complete course in e.g a 60 kg man it comes out to be 12 months of 20mg, once daily or 6 months of 20mg, twice daily. The chances of relapse are more likely, if the course is incomplete.
I normally start Isotretinoin at 20mg and make it 40 mg after a month, which i continue till the total cumulative dose has been given (i.e 120-140mg/kg)
Moreover, while you are on oral isotretinoin, your Lipid profile and Liver function tests need to be monitored at regular intervals, therefore it is all the more necessary to follow up with a dermatologist while you are on Isotretinoin.
In addition to Isotretinoin, the oral antibiotic (Azilide) can be continued for 4-12 weeks depending on the response.
In addition to oral retinoids and oral antibiotics you must also use topical antiacne remedies e.g benzoyl peroxide gel OR Clindamycin+nicotinamide gel.
regards
For severe acne OR for acne unresponsive to traditional anti-acne medications, Isotretinoin is the drug of choice. It the only drug which offers any chance of long term cure and after a full course of isotretinoin significant number of people never have a recurrence of there acne. However it should be given in the right dose and for the right duration.
Total Cumulative dose of Isotretinoin that should be taken is 120-140mg/kg.
For a complete course in e.g a 60 kg man it comes out to be 12 months of 20mg, once daily or 6 months of 20mg, twice daily. The chances of relapse are more likely, if the course is incomplete.
I normally start Isotretinoin at 20mg and make it 40 mg after a month, which i continue till the total cumulative dose has been given (i.e 120-140mg/kg)
Moreover, while you are on oral isotretinoin, your Lipid profile and Liver function tests need to be monitored at regular intervals, therefore it is all the more necessary to follow up with a dermatologist while you are on Isotretinoin.
In addition to Isotretinoin, the oral antibiotic (Azilide) can be continued for 4-12 weeks depending on the response.
In addition to oral retinoids and oral antibiotics you must also use topical antiacne remedies e.g benzoyl peroxide gel OR Clindamycin+nicotinamide gel.
regards
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