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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suffering From Fits. Taking Zeptol-cr. Will It Have Any Side-effects On Fertility?

I am 25 years old female. I got fits 4 years ago and consulted doctor. I had undergone EEG and other tests. All are normal. I have taken Zeptol CR 300 for almost 3 years and stopped taking tablets. After a year, I got fits again. Now I am taking Zeptol CR 300 daily. I am married and worried if Zeptol has any side effects and especially Pregnancy. I am taking Folic acid tablets. Please let me know if these tablets will create any problems during pregnancy and after delivery.
Fri, 28 Dec 2012
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Neurologist, Surgical,  's  Response
Hi Venkat,

Patient's on Zeptol - (carbamazepine) have a 2-10 fold increased risk of developing neural tbve defects in the fetus. However, this medicine has been viewed as the drug of choice by many when the patient is pregnant. Therefore this is more safe than the other medications. Before conception, it is advisable to take Folic acid in order to prevent occurance of neural tube defects as has been done by your doctor. The greater risk in pregnancy to both you and your child is the occurence of seizures and therfore you will need to be closely followed up by your doctor from before conception right through delivery.
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Suffering From Fits. Taking Zeptol-cr. Will It Have Any Side-effects On Fertility?

Hi Venkat, Patient s on Zeptol - (carbamazepine) have a 2-10 fold increased risk of developing neural tbve defects in the fetus. However, this medicine has been viewed as the drug of choice by many when the patient is pregnant. Therefore this is more safe than the other medications. Before conception, it is advisable to take Folic acid in order to prevent occurance of neural tube defects as has been done by your doctor. The greater risk in pregnancy to both you and your child is the occurence of seizures and therfore you will need to be closely followed up by your doctor from before conception right through delivery.