Hello and welcome to Healthcare Magic. Thanks for your query. I understand that you must be quite worried about your mother s recent symptoms. You have mentioned that she is taking 2 drugs and wish to know about the possible drug interactions, but unfortunately, you haven t given any details about the drugs. So, please mention the drug names, dosages and the duration for which she is on these drugs, so that we can see if there could be possible drug interactions. The symptoms that you have described briefly (such as paranoia, fears / beliefs that people may be harming her) could point to a type of mental disorder called psychosis . Now, the reasons for developing psychotic symptoms could be many, like underlying brain / neurological problems, metabolic abnormalities, dementia, etc. The first step in managing such a scenario is to have a detailed medical evaluation including a neurological evaluation, so that the cause of her problems can be identified. So, I would suggest that you take her to a doctor as early as possible for a detailed evaluation and further management. Wish you all the best. Regards, Dr. Jonas Sundarakumar Consultant Psychiatrist