Dear Dr, I suffer from mouth ulcers but they tend to clear in approx 2 weeks, but now have a large ulcer at the back of my tongue which has been there approx 6 to 7 weeks. I am going for a biopsy this coming Monday. I am a long standing heart patient since 1985 and presently am taking 40mg of Nicorandil daily along with the other many heart drugs. Have been taking Nicorandil for as long as I have suffered with mouth ulcers. I also have an anal fissure so worry a little when I hear of anal cancer. Will be asking my GP what alternatives may be out there to replace Nicorandil. Any comments please? Yours, Anthony Suart.