What do you recommend for HRT: Prempro or prometherine and estradiol? and at what dose? I am 56, last August I stopped Nordette BCP treatment after 5 years for peri menopausal symptoms due to developing nausea, right eye pain, sternal and shoulder pain, and increase in blood pressure for two months. My LMP was also last August. I felt a lot better the next few months with normal Bp, though my sternal pain continued resulting in a negative echocardiogram. I had return of mild hot flashes and insomnia though. Over the last several months, joint and muscle pain and fatigue, negative serology for RA, ANA, etc. with recommendation for HRT.