HI, I understand your query, Osteoarthrits is a condition caused by degenerative changes in joint due to old age/ joint injury.This results in destruction of cartilage in joints who have a protective action for the bones making the joint. The movements become painful there is swelling/ painful movements. * All the three pills you have been taking (Meloxicam,Celebrex,Ibuprofen)are Nonsteroidal antinflammatory drugs- They are good for pain control in osteoarthritis. - Alternatively local injectable corticosteroids are other option These drugs are to be taken to control pain in acute condition -Along with rest to the affected joint. * The management of the condition by - - weight reduction, - regular exercises & having an active life. -learn relaxation techniques. - specific exercises for the joint involved( physiotherapy) -developing a healthy life style( eating, exercises, relaxation, meditation. Help in having painless active life with least possible medicines. * surgery is essential in non responding patients. Consult an orthopedic doctor for guidance / advise. thanks.