What herbal remedy can I take for depression. I just turned 50 and I have had some personal issues contributing to my depression . I am currently looking for work with no luck. I am a type 2 diabetic, but not on any medication for it, because my last A1C was reasonable and my Endocrinolgist advised I discontinue using Victoza. However, I gained all the weight back - nearly 30 pounds that I lost last year, because I am using food as comfort to deal with my depression and stopped using Victoza, which helped me lose the wight. I have started exercising and meditation, but I still feel down. Can you advise anything that doesn t include Xanax or Prozac, which I have taken in the past and stopped because it made me gain weight? Black cohosh maybe.