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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Remedy For Severe Anemia

Hallo, My friend (age 29) for over a year has severe anemia, but at the moment the doctors don\'t know what it is. At the beginning they suspected the myelodysplastic syndrome. The bone marrow biopsy made 3 times, didn\'t reveal any abnormalities. Lymphoma, leukemia, cancer and proxysmal nocturnal hemoglobinuria, celiake and ednocrine diseases have been exluded. Gastroscopy, colonoscopy and abdominal ultrasound also came out in ok. Viscerial arteriografia also unchenged, thickening of the iheum and jejunum was only noticed.My friend has a low level of iron and potassium but the intravenous administration minimally raises the hemoglobin level. It was initialy enough to roll blood once every 3-4 weeks, but since 3 months administration of two units of blood rises hemoglobin for only 0,5 while it can decrease during the day even by up to 1. My friend occasionally complains of pain in the lower spine and kidney area. She also suffersasthma and is allergic. Today the doctor told her that he could only give her blood and iron and wait as the illness developes. If it\'s possible, I\'d like to consult. I can send a mail with the results.Best regards Justyna from Poland
Mon, 1 Jun 2015
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Pathologist and Microbiologist 's  Response
Hi I did review your concern. Can you please send me a direct question with the complete details of her lab reports. I can answer better. i am thinking of possibilities like enzyme defects or hemoglobinopathies. sideroblastic anemia and other rare causes of anemia.
Waiting for your reply.
good luck.
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Pathologist and Microbiologist Dr. Geethanjali Bhas's  Response
In order to make a diagnosis of the type and cause of anemia I would require the Complete blood count, especially the MCV ( mean corpucular volume values) & RDW ( red cell distribution width). This has to be interpreted in conjunction with the peripheral blood smear. Is there any possibility of chronic blood loss for your friend ? Since your friends anemia is chronic & refractory we would require more details of the investigations that were done . Has a test for G6PD deficiency been done for your friend ( glucose -6 phosphate dehydrogenase ) ? This is an enzyme in the red blood cells which if deficient can cause anemia. From your question I presume that almost all tests have been done for your friend. Awaiting further information. Warmest regards Dr Geetha
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Suggest Remedy For Severe Anemia

Hi I did review your concern. Can you please send me a direct question with the complete details of her lab reports. I can answer better. i am thinking of possibilities like enzyme defects or hemoglobinopathies. sideroblastic anemia and other rare causes of anemia. Waiting for your reply. good luck.